Health encyclopaedia - Alphabetical Topic List

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| N | | O | | P | | Q | | R | | S | | T | | U | | V | | W | | X | | Y |

Symptoms of Androgen insensitivity syndrome

In AIS, although the body is insensitive to androgens, it is responsive to oestrogens, and is affected by the small amount of oestrogen produced by the testes or by the oestrogen replacement therapy given if the testes are removed before puberty. 

When there is CAIS the outward appearance is completely female and individuals are invariably brought up as girls however they have are no ovaries, fallopian tubes or uterus and the vagina is shorter than normal or absent. Internally they have un-descended testes which don’t work.

In CAIS female development takes place at puberty but there is no menstruation (periods) and no possibility of conceiving children. At puberty there will therefore be normal female breast development but minimal pubic or body hair. 

The genital appearance of newborns with PAIS varies; many babies are brought up as girls, although some with a more male genital appearance may be brought up as boys.