Health encyclopaedia - Alphabetical Topic List

| A | | B | | C | | D | | E | | F | | G | | H | | I | | J | | K | | L | | M |
| N | | O | | P | | Q | | R | | S | | T | | U | | V | | W | | X | | Y |

Causes of Cancer of the breast, male

There are a number of factors that are thought to increase the risk of breast cancer in men. These include:

  • A close relative (male or female) with a history of breast cancer. The risk is higher if several close relatives are involved, if the relative was under 40, or if they had it in both breasts. About 5-10% of cases are thought to have a genetic basis.
  • A rare genetic condition call Klinefelter’s syndrome, which means the man has an extra female chromosome. 
  • High oestrogen (female sex hormone) levels; this is rare in men but can be caused by conditions such as liver damage and obesity. 
  • Low androgen (male hormone) levels. This can be caused by genetic conditions such as Klinefelter’s syndrome; mumps, liver failure or damage to hormone-producing glands; or due to injury to the testicles. 
  • Exposure to high levels of radiation (other than normal background radiation), especially when young. This may be as a result of high radiation in the workplace, or because of previous treatment with radiation in the chest area, for example for Hodgkin’s lymphoma or lung cancer.