Health encyclopaedia - Alphabetical Topic List

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Treatment of Cold sore

The most common treatment for cold sores is the drug aciclovir. It stops the virus from reproducing by interfering with its DNA.

Aciclovir is available as a cream for the treatment of cold sores on the lips. The cream should be applied 5 times a day for 5 days. Aciclovir can also be taken by mouth in tablet form (for recurrent, severe attacks). Another drug called valacyclovir is also sometimes prescribed as tablets.

Balm mint extract and tea tree oil may also help with pain and itching.

Treat any pain by taking paracetamol or applying witch hazel to the sore. A topical (applied to the skin) anaesthetic may be prescribed by your doctor. See your pharmacist for advice on pain relief. 

Don’t pick cold sores because this may spread the virus to other parts of the body, or allow the sore to become infected.

Drink plenty of fluids to keep hydrated, and avoid salty, spicy or acidic foods and drinks, which may irritate the sore. Eating soft foods such as soup may be less painful, as there is less need to chew and move the mouth.