Treatment of Diabetes insipidus

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In order to treat diabetes insipidus, it is important to find the cause.

When diabetes insipidus is caused by lack of ADH, it can be treated with a substance called desmopressin. This is a manmade version of ADH, and is more powerful than the ADH that is naturally produced in the body. It can be given as tablets or as a nasal spray, because it can be absorbed through the mucous in the nose.

In mild cases of this type of diabetes insipidus, it may be possible to treat the condition simply by taking more fluids.

Nephrogenic diabetes insipidus cannot be treated with desmopressin. A diuretic drug such as thiazide, and a very low salt diet, can help to reduce the amount of urine being made by up to half.

If nephrogenic diabetes insipidus is being caused by medications, stopping these medicines may help, but you should not stop medication without discussing this with your GP.

Hereditary nephrogenic diabetes insipidis is treated by giving more fluids, and drugs including diuretics and anti-inflammatories.