Causes of Leukoplakia

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Leukoplakia is always caused by irritation of the tissues in the mouth. The irritation may be from rough teeth, fillings, crowns, dentures and so on, or it may be as a result of smoking or other tobacco use. This is known as smokerâ€™s keratosis. Smoking a pipe or chewing tobacco in forms such as paan masala or gutkha give a high risk of developing leukoplakia.

Excessive alcohol consumption or persistent cheek chewing may also cause leukoplakia.