Health encyclopaedia - Alphabetical Topic List

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Marfan syndrome

Marfan syndrome is a genetic disorder of the connective tissue, which can involve many  areas of the body such as the heart, lungs, skin, skeleton and eyes.

The syndrome is rare, affecting 1 in 10,000 of the population.  It is sometimes referred to as an autosomal dominant condition, meaning that people with Marfan syndrome have a 50% chance of passing it on to one of their children.  75% of cases are a result of inheritance from a parent who also has the disorder; in 25% of cases spontaneous mutation is the cause.