Health encyclopaedia - Alphabetical Topic List

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Causes of Multiple sclerosis

No single cause has been identified and many factors are probably involved

  • MS is not hereditary but can occur in more than one family member, suggesting a genetic predisposition. You are more likely to get MS if other people in your family have it, especially a brother or sister.
  • An environmental agent such as a virus may be involved although no single virus has been identified as being responsible.
  • Environmental factors may trigger MS in susceptible people, amongst the environmental factors suggested are diet, stress, trauma and nutrition.
  • MS is more common in people of certain tissue types (HLA groups);
  • Evidence suggests MS may result from an auto-immune process (where the body attacks its own cells or tissues)
  • The incidence of MS increases in countries further from the equator. It is 5 times more common in temperate zones than in the tropics.