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Myasthenia gravis

The defining feature of myasthenia gravis is muscle weakness that fatigues - in other words the muscles weaken more rapidly on use than is normal.

The symptoms typically worsen towards the end of the day and after exercise. Myasthenia gravis affects about one person in every 10,000 in the UK. The disorder can start at any age from childhood onwards and the chance of developing it increases with age. In the younger age group, women are affected about twice as often as men are. However, in later life it is commoner in men than women.

The prognosis of myasthenia gravis is good. Using the array of therapies that are now available, more than 90% of patients make almost full recoveries.