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Symptoms of Rhesus factor disease

As the baby’s blood is broken down, bilirubin (a bile pigment) is produced. In very high levels this can cause severe brain damage, with paralysis, learning difficulties, blindness and deafness.

The child is born deeply jaundiced with an enlarged liver and spleen and a low haemoglobin level in the blood (see Anaemia).

In the most severe cases, the foetus dies in the uterus, usually after the 28th week.

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