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Causes of Sjogren's syndrome
Sjögren's syndrome occurs most often in people with a particular tissue typing (HLA B8 DR3). It tends to occur in disorders such as:
- rheumatoid arthritis,
- lupuserythematosus,
- myastheniagravis,
- dermatitis, and
- herpetiformis or autoimmune liver or thyroid disease.
About 25 to 50% of people with rheumatoid arthritis have Sjögren's syndrome and 90% of those affected are women, usually middle-aged and often post-menopausal.
