Health encyclopaedia - Alphabetical Topic List健康百科全书-按字母顺序排列的主题清单

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Treatment of Haemophilia治疗血友病

Factor VIII is a protein substance, a globulin.因子VIII是一种蛋白物质,球蛋白。 The substance can be isolated from donated blood and given to haemophiliacs to control their bleeding tendency.物质可以被孤立从捐赠的血液给血友病患者,控制其出血倾向。 Unfortunately, factor VIII is active only for a short period – it loses half its activity after only 12 hours – so repeated injections are necessary.不幸的是,因子VIII是积极只为在短期内â € “它失去了一半的活动后,只有12个小时â € ” ,所以重复注射是必要的。

The severity of haemophilia varies with the level of natural factor VIII activity in the individual.严重的血友病不同程度的自然因子VIII活动在个别。 In severe cases the levels are less than five per cent of normal, and they may be less than two per cent of normal.在严峻的情况下,各级少于百分之五正常,他们可能少于2 %的正常。 The level of clotting-factor activity determines the need for replacement therapy, and the dosage.水平凝血因子活性的决定需要替代疗法,和剂量。 The replacement factors are given by slow injection into a vein.更换的因素,给出了由缓慢注入静脉。

Injections may be given on a regular basis, this helps prevent bleeding and minimise joint damage, or only when the bleeding occurs.A fairly recent development involves treatment is with genetically engineered factor VIII, ‘recombinant’ clotting factor, rather than donated human factor VIII.注射可考虑对定期的基础上,这有助于防止出血及减少关节损害,或只有当出血occurs.a相当近期的发展,涉及治疗与基因工程因子VIII , â € 〜 recombinantâ € ™凝血因子,而非捐赠人的因素八。