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Causes of Irritable bowel syndrome原因肠易激综合征

The precise cause of irritable bowel syndrome is unknown.确切的原因肠易激综合征是未知之数。 The condition often begins during a period of emotional stress and symptoms worsen in stressful situations.条件往往是开始期间,情绪压力和症状恶化,在没有压力的情况。

Up to 60 per cent of people with the syndrome have psychological symptoms such as anxiety and depression.高达60 %的人与综合征有心理症状,如焦虑和抑郁。 The disorder sometimes develops after a gastrointestinal infection.无序,有时发展后,胃肠道感染。 An increased sensitivity or intolerance to certain foods, may also contribute.增加的敏感性或不容忍某些食品,也可能有助于。

It may result from exaggerated contractions of the muscles in the intestinal walls.它可能会导致从夸张的收缩肌肉,在肠道的墙壁。 These abnormal contractions can be tested by placing pressure-sensing devices in the colon.这些不正常的收缩,可以测试配售的压力传感装置在结肠。 The colon muscle of a person with IBS begins to spasm after only mild stimulation and is more sensitive and reactive than usual.结肠肌肉一个人与IBS的开始痉挛后,只有轻微的刺激,是较为敏感和反应较正常。

The chemical transmitter that mediates the change to pressures within the bowel has been identified as serotonin, a chemical found in the brain as well as in the bowel.化学发射介导改变的压力,内部的肠易激已被确定为羟色胺,化学,发现在大脑中,以及在肠易激。 Ninety-five per cent of serotonin is found in the bowel. 95 %的羟色胺是发现,在肠易激。 In the bowel, serotonin is mainly concerned with the contraction of the smooth muscle in the bowel wall.在肠道,羟色胺,主要是关注与收缩的平滑肌,在肠壁。 The exact mechanism is not known but serotonin receptors are thought not to function properly in IBS.确切的机制是不知道,但羟色胺受体被认为是不正常,在肠易激综合征。