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Causes of Paget's disease原因Paget病的

Like other cells in our bodies, bone cells are constantly dying and being replaced by new ones.像其他细胞在我们的机构,骨细胞不断死亡和被取代的新个案。 With paget’s disease of bone, this process is disrupted.与pagetâ € ™病骨,这个过程是破坏。 Bone is broken down at a faster rate than normal.骨是细分在一个更快的速度较正常。 In response to the speedy loss of bone cells, the body makes new bone cells very quickly.在反应迅速的损失骨细胞,人体,使新骨细胞非常快。 These are then badly ‘woven’ back into the bone, and as a result, bones are weaker.这些都是那么急切â € 〜 wovenâ € ™回复到骨,和作为一个结果,骨头较弱。 They are also bigger, because the body has produced more new bone cells than it needs.他们也更大,因为身体产生了更多新的骨细胞,比它的需要。

The actual cause of paget’s disease of bone is not known.实际的原因pagetâ € ™病骨是不知道。 Evidence shows that it might be heredity (run in the family); up to 4 in 10 people with Paget’s disease of bone have a close relative who also develops the disease.有证据表明,它可能是遗传(运行在家庭中) ;最多4个在10人与pagetâ € ™病骨有密切的相对谁也发展了这种疾病。

A gene (something which is passed down from your parents to determine your body’s characteristics) has been identified that can make it more likely for you to get the disease.一个基因(这是传下来的从你的父母,以确定您的bodyâ € ™ s特色)已被确定可以使它更可能让您得到的疾病。 It could also be because the bone is infected with a virus that affects it in some way, but this is a controversial theory, which has been hard to prove.它也可能是因为骨是感染了病毒影响,它以某种方式,但是这是一个有争议的理论,已很难证明。